Jae-Seong Yang

Graduate Student ; Ph.D. course in I-BIO Program

Structural Bioinformatics Laboratory and Center for Superfunctional Materials

Pohang University of Science and Technology,

San 31, Hyoja-dong, Pohang , Kyungbuk, 790-784, South Korea

Tel : 82-54-279-8171, E-mail : destine(at)postech.ac.kr

B.S. Life Science & Computer Science from POSTECH


Publications

Journal Articles

2011

Cho NH, Cheong TC, Min JH, Wu JH, Lee SJ, Kim D, Yang JS, Kim S, Kim YK, Seong SY A multifunctional core-shell nanoparticle for dendritic cell-based cancer immunotherapy.  Nat Nanotechnol. 2011 Sep 11.

Yang JS, Nam HJ, Seo M, Han SK, Choi Y, Nam HG, Lee SJ, Kim S. OASIS: Online Application for the Survival Analysis of Lifespan Assays Performed in Ageing Research.  PLoS ONE. 2011 July 19

Jeon J, Jeong JH, Baek JH, Koo HJ, Park WH, Yang JS, Yu MH, Kim S, Pak YK, Network clustering revealed the systemic alterations of mitochondrial protein expression,. Accepted in PLoS Computational Biology 2011

Park S, Yang JS, Shin YE, Park J, Jang SK, Kim S, Protein localization as a principal feature of the etiology and comorbidity of genetic diseases,. Accepted in Mol Syst Biol 2011

Jeon J, Nam HJ, Choi Y, Yang JS, Hwang J, Kim S, Molecular evolution of protein conformational changes revealed by a network of evolutionarily-coupled residues. Mol Biol Evol 2011. (PMID: 21470969)

2010

Choi YS, Han SK, Kim J, Yang JS, Jeon J, Ryu SH, Kim S. ConPlex: a sever for the evolutionary conservation analysis of protein complex structures.  Nucleic Acid Res 2010

Yang JS+, Kim JT+, Jeon J, Park HS, Kang GH, Park KS, Lee HK, Kim S*, Cho YM*. +Joint first authors * Corresponding authors Changes in Hepatic Gene Expression upon Oral Administration of Taurine-Conjugated Ursodeoxycholic Acid in ob/ob Mice.  PLoS ONE. 2010

Cho BA, Cho NH, Min CK, Kim SY, Yang JS, Lee JR, Jung JW, Lee WC, Kim K, Lee MK, Kim S, Kim KP, Seong SY, Choi MS, Kim IS. Global gene expression profile of Orientia tsutsugamushi.  Proteomics. 2010

Lee GH, Ahn T, Kim DS, Park SJ, Lee YC, Yoo WH, Jung SJ, Yang JS, Kim S, Muhlrad A, Chae SW, Kim HR, Chae HJ. Bax Inhibitor-1 increases cell adhesion through actin polymerization: The involvement of calcium and actin binding.  Mol Cell Biol. 2010

2009

Jeon J, Yang JS, Kim S. Integration of evolutionary features for the identification of functionally important residues in Major Facilitator Superfamily (MFS) transporters.  PLoS Comput Biol. 2009 Oct;5(10):e1000522. Epub 2009 Oct 2.

Choi YS, Yang JS, Choi Y, Ryu SH, Kim S. Evolutionary conservation in multiple faces of protein interaction.  Proteins. 2009 Oct;77(1):14-25.

Park S, Yang JS, Jang SK, Kim S. Construction of Functional Interaction Networks through Consensus Localization Predictions of the Human Proteomed  J Proteome Res. 2009 Jul;8(7):3367-76.

2008

Min CK, Bang SY, Cho BA, Choi YH, Yang JS, Lee SH, Seong SY, Kim KW, Kim S, Jung JU, Choi MS, Kim IS, Cho NH. Role of Amphipathic Helix of a Herpesviral Protein in Membrane Deformation and T Cell Receptor Downregulation.  PLoS Pathog. 2008 Nov;4(11):e1000209. Epub 2008 Nov 21.  PMID: 19023411 [PubMed]

Min C, Yang JS, Choi M, Kim I, Cho N. Genome-based construction of the metabolic pathways of Orientia tsutsugamushi and comparative analysis within the Rickettsiales order.  Comparative and Functional Genomics. 2008 Accepted. [Journal]

2007

Choi S*, Jeon J*, Yang JS, Kim S. *Joint first authors Common occurrence of internal repeat symmetry in membrane proteins  Proteins: Structure, Function, and Bioinformatics  2007 Oct 11; PMID: 17932930 [PubMed]

Kim YK, Park HW, Yang JS, Oh SY, Chang YS, Shin ES, Lee JE, Kim S, Gho YS, Cho SH, Min KU, Kim YY. Association and functional relevance of E237G, a polymorphism of the high-affinity immunoglobulin E-receptor ¥â chain gene, to airway hyper-responsiveness  Clinical & Experimental Allergy  2007 Apr;37(4):592-598; PMID: 17430357 [Journal], [PubMed]

2006

Choi Y, Yang J, Ryu SH, Kim S. Retrieving protein domain encoding DNA sequences automatically through database cross-referencing  Bioinformatics and Biosystems  2006 Jun 1;1:95-98.

2005

Sung Geun Lee, Jae Seong Yang, Il Kyung Chung, Yang Seok Kim, BINGO: Biological Interpretation Through Statistically and Graph-theoretically Navigating Gene Ontology.  Molecular & Cellular Toxicology  2005 1(4):281-283;1:95-98. [Journal] [PDF]

2003

Sung Geun Lee, Jae Seong Yang, Wan Seon Lee, Miyoung Shin, Yang Seok Kim, Extraction of Biological Contexts and Ontological DAG Structures from Gene Groups Using GO Term Distribution.  Genome Informatics  2003 14:683-684. [Journal] [PDF]

Conference Posters

Jae-Seong Yang, Dong-Sic Choi , Jou-Hyun Jeon, Yong Song Gho, and Sanguk Kim, Identification of the functional network components in tumor derived microvesicles.  The 8th International Conference of Korean Society for Bioinformatics  2007

Jae-Seong Yang, Jou-hyun Jeon, Jinho Kim and Sanguk Kim, Detecting the ligand selectivity of sub-family proteins by using evolutionary conserved and functionally coevolved residues.  VII European Symposium of the Protein Society  2007


My Mentors

Sanguk Kim, Structural Bioinformatics Laboratory@POSTECH

Kwang S. Kim, Center for Superfunctional Materials@POSTECH

Sung Geun Lee, ISTECH Inc.

Young-Yun Kong, Development & Disease modeling Laboratory@SNU

Youngsook Lee, The Plant Cell Biology Laboratory@POSTECH

Hong Gil Nam, Nam's Laboratory@POSTECH

Past and Current Collaborators

Hyunjoon Kim, Developmental Biology Laboratory@POSTECH

Sungwoo Park, Programming Language Laboratory@POSTECH

Bon-Kyoung Koo, Immunology & Disease modeling Laboratory@POSTECH

Min-Chul Kwon, Immunology & Disease modeling Laboratory@POSTECH

Dong Sic Choi, Lab of Intercelluar communication network@POSTECH

Yoon-Keun Kim, Laboratory ¾Ë·¹¸£±â ¹× ÀÓ»ó¸é¿ª¿¬±¸½Ç@POSTECH

SBI Members, Structural Bioinformatics Laboratory@POSTECH


Interesting Groups

Regev Laboratory, The Regev Laboratory@BROAD Institute

Marcotte Laboratory, The Marcotte Laboratory@University of Texas at Austin

Mootha Laboratory, Systems Approaches to Mitochondrial Biology@Harvard Medical School

Ideker Laboratory, Network and Systems Biology@UCSD

MLG Laboratory, Machine Learning Group@POSTECH

Baker Laboratory, The Baker Laboratory@University of Washington

Vicsek Laboratory, The Vicsek Laboratory@ELTE

Hughes Laboratory, The Hughes Laboratory@University of Toronto

Ruppin Laboratory, The Ruppin Laboratory@Tel Aviv University

Aebersold Group, The Aebersold Group@ETH Zurich