Graduate Student ; Ph.D. course in I-BIO Program
Structural Bioinformatics Laboratory and Center for Superfunctional Materials
Pohang University of Science and Technology,
San 31, Hyoja-dong, Pohang , Kyungbuk, 790-784, South Korea
Tel : 82-54-279-8171, E-mail : destine(at)postech.ac.kr
B.S. Life Science & Computer Science from POSTECH
Publications
Journal Articles
Cho NH, Cheong TC, Min JH, Wu JH, Lee SJ, Kim D, Yang JS, Kim S, Kim YK, Seong SY A multifunctional core-shell nanoparticle for dendritic cell-based cancer immunotherapy. Nat Nanotechnol. 2011 Sep 11.
Yang JS, Nam HJ, Seo M, Han SK, Choi Y, Nam HG, Lee SJ, Kim S. OASIS: Online Application for the Survival Analysis of Lifespan Assays Performed in Ageing Research. PLoS ONE. 2011 July 19
Jeon J, Jeong JH, Baek JH, Koo HJ, Park WH, Yang JS, Yu MH, Kim S, Pak YK, Network clustering revealed the systemic alterations of mitochondrial protein expression,. Accepted in PLoS Computational Biology 2011
Park S, Yang JS, Shin YE, Park J, Jang SK, Kim S, Protein localization as a principal feature of the etiology and comorbidity of genetic diseases,. Accepted in Mol Syst Biol 2011
Jeon J, Nam HJ, Choi Y, Yang JS, Hwang J, Kim S, Molecular evolution of protein conformational changes revealed by a network of evolutionarily-coupled residues. Mol Biol Evol 2011. (PMID: 21470969)
2010Choi YS, Han SK, Kim J, Yang JS, Jeon J, Ryu SH, Kim S. ConPlex: a sever for the evolutionary conservation analysis of protein complex structures. Nucleic Acid Res 2010
Yang JS+, Kim JT+, Jeon J, Park HS, Kang GH, Park KS, Lee HK, Kim S*, Cho YM*. +Joint first authors * Corresponding authors Changes in Hepatic Gene Expression upon Oral Administration of Taurine-Conjugated Ursodeoxycholic Acid in ob/ob Mice. PLoS ONE. 2010
Cho BA, Cho NH, Min CK, Kim SY, Yang JS, Lee JR, Jung JW, Lee WC, Kim K, Lee MK, Kim S, Kim KP, Seong SY, Choi MS, Kim IS. Global gene expression profile of Orientia tsutsugamushi. Proteomics. 2010
Lee GH, Ahn T, Kim DS, Park SJ, Lee YC, Yoo WH, Jung SJ, Yang JS, Kim S, Muhlrad A, Chae SW, Kim HR, Chae HJ. Bax Inhibitor-1 increases cell adhesion through actin polymerization: The involvement of calcium and actin binding. Mol Cell Biol. 2010
2009Jeon J, Yang JS, Kim S. Integration of evolutionary features for the identification of functionally important residues in Major Facilitator Superfamily (MFS) transporters. PLoS Comput Biol. 2009 Oct;5(10):e1000522. Epub 2009 Oct 2.
Choi YS, Yang JS, Choi Y, Ryu SH, Kim S. Evolutionary conservation in multiple faces of protein interaction. Proteins. 2009 Oct;77(1):14-25.
Park S, Yang JS, Jang SK, Kim S. Construction of Functional Interaction Networks through Consensus Localization Predictions of the Human Proteomed J Proteome Res. 2009 Jul;8(7):3367-76.
2008Min CK, Bang SY, Cho BA, Choi YH, Yang JS, Lee SH, Seong SY, Kim KW, Kim S, Jung JU, Choi MS, Kim IS, Cho NH. Role of Amphipathic Helix of a Herpesviral Protein in Membrane Deformation and T Cell Receptor Downregulation. PLoS Pathog. 2008 Nov;4(11):e1000209. Epub 2008 Nov 21. PMID: 19023411 [PubMed]
Min C, Yang JS, Choi M, Kim I, Cho N. Genome-based construction of the metabolic pathways of Orientia tsutsugamushi and comparative analysis within the Rickettsiales order. Comparative and Functional Genomics. 2008 Accepted. [Journal]
2007Choi S*, Jeon J*, Yang JS, Kim S. *Joint first authors Common occurrence of internal repeat symmetry in membrane proteins Proteins: Structure, Function, and Bioinformatics 2007 Oct 11; PMID: 17932930 [PubMed]
Kim YK, Park HW, Yang JS, Oh SY, Chang YS, Shin ES, Lee JE, Kim S, Gho YS, Cho SH, Min KU, Kim YY. Association and functional relevance of E237G, a polymorphism of the high-affinity immunoglobulin E-receptor ¥â chain gene, to airway hyper-responsiveness Clinical & Experimental Allergy 2007 Apr;37(4):592-598; PMID: 17430357 [Journal], [PubMed]
2006Choi Y, Yang J, Ryu SH, Kim S. Retrieving protein domain encoding DNA sequences automatically through database cross-referencing Bioinformatics and Biosystems 2006 Jun 1;1:95-98.
2005Sung Geun Lee, Jae Seong Yang, Il Kyung Chung, Yang Seok Kim, BINGO: Biological Interpretation Through Statistically and Graph-theoretically Navigating Gene Ontology. Molecular & Cellular Toxicology 2005 1(4):281-283;1:95-98. [Journal] [PDF]
2003Sung Geun Lee, Jae Seong Yang, Wan Seon Lee, Miyoung Shin, Yang Seok Kim, Extraction of Biological Contexts and Ontological DAG Structures from Gene Groups Using GO Term Distribution. Genome Informatics 2003 14:683-684. [Journal] [PDF]
Conference Posters
Jae-Seong Yang, Dong-Sic Choi , Jou-Hyun Jeon, Yong Song Gho, and Sanguk Kim, Identification of the functional network components in tumor derived microvesicles. The 8th International Conference of Korean Society for Bioinformatics 2007
Jae-Seong Yang, Jou-hyun Jeon, Jinho Kim and Sanguk Kim, Detecting the ligand selectivity of sub-family proteins by using evolutionary conserved and functionally coevolved residues. VII European Symposium of the Protein Society 2007
My Mentors
Sanguk Kim, Structural Bioinformatics Laboratory@POSTECH
Kwang S. Kim, Center for Superfunctional Materials@POSTECH
Sung Geun Lee, ISTECH Inc.
Young-Yun Kong, Development & Disease modeling Laboratory@SNU
Youngsook Lee, The Plant Cell Biology Laboratory@POSTECH
Hong Gil Nam, Nam's Laboratory@POSTECH
Past and Current Collaborators
Hyunjoon Kim, Developmental Biology Laboratory@POSTECH
Sungwoo Park, Programming Language Laboratory@POSTECH
Bon-Kyoung Koo, Immunology & Disease modeling Laboratory@POSTECH
Min-Chul Kwon, Immunology & Disease modeling Laboratory@POSTECH
Dong Sic Choi, Lab of Intercelluar communication network@POSTECH
Yoon-Keun Kim, Laboratory ¾Ë·¹¸£±â ¹× ÀÓ»ó¸é¿ª¿¬±¸½Ç@POSTECH
SBI Members, Structural Bioinformatics Laboratory@POSTECH
Interesting Groups
Regev Laboratory, The Regev Laboratory@BROAD Institute
Marcotte Laboratory, The Marcotte Laboratory@University of Texas at Austin
Mootha Laboratory, Systems Approaches to Mitochondrial Biology@Harvard Medical School
Ideker Laboratory, Network and Systems Biology@UCSD
MLG Laboratory, Machine Learning Group@POSTECH
Baker Laboratory, The Baker Laboratory@University of Washington
Vicsek Laboratory, The Vicsek Laboratory@ELTE
Hughes Laboratory, The Hughes Laboratory@University of Toronto
Ruppin Laboratory, The Ruppin Laboratory@Tel Aviv University
Aebersold Group, The Aebersold Group@ETH Zurich